We have reported the first case of antenatal CCHFV infection and neonatal death
that has been well documented using molecular genetic techniques. The obtained
data revealed that CCHFV easily penetrated the placental barrier without the significant selection of viral populations. Therefore, for pregnant women with CCHF, the risk of CCHFV-induced death of the
fetus is extremely high; this risk must be taken into account in anti-epidemic
planning to minimize the incidence of this serious and potentially lethal
illness.